The present study tries to find out the relationship between self esteem and teaching skills of arts and science prospective teachers. Survey method is adopted for this study. A sample of 120 Arts and Sciences B. Ed students (40 male & 80 female) was selected from the Malappuram Districts of Kerala. Self Esteem Questionnaire developed by S. Karunanidhi is used to assess the level of self esteem and the score given by teacher educators and school mentors is used to assess the teaching skills of prospective teachers. Mean, SD, t-test & correlation are employed to analyze the data. Findings show that there is significant correlation between self esteem and teaching skills among prospective teachers. However, there exists no significant difference in the self esteem and teaching skills of arts and science prospective teachers. Also, there is no significant difference in the self esteem and teaching skills of male and female prospective teachers. It can be concluded that self esteem plays an important role in developing effective teaching skills among prospective teachers. So, the self esteem of student teachers should be boost up by all levels and the teacher educators should ensure proper provisions to develop self esteem in student teachers.