Socio-economic status is a construct that reflects one’s access to collectively desired resources, material goods, money, power, occupation, healthcare, leisure time, or educational opportunities which is also related to the academic stress of students. Main objective of the present study was to find out the difference between academic stresses of students belonging to different socio-economic status. A sample of 200 students studying in 6 senior secondary schools of Samastipur (Bihar, India) was selected through simple random sampling method. Personal datasheet of students was used to determine their socio-economic status and self-developed Academic Stress Questionnaire (ASQ) was used for the data collection. The result revealed that students belonging to low socio-economic status have higher level of academic stress as compared to the students belonging to high socio-economic status, especially boys. However Girls belonging to different socioeconomic status didn’t exhibit any significant difference in their academic stress. The findings also revealed that personal inadequacy and inadequate study facilities causes more academic stress among students belonging to low socio-economic status. In the case of boys belonging to low socio-economic status, inadequate study facilities causes more academic stress while in the case of girls belonging to low socio-economic status, personal inadequacy causes more academic stress. It was concluded that socio-economic status has a significant impact on the academic stress as low socio-economic status and its correlates, such as lower education, poverty, and poor health, ultimately affect our society as a whole. So it is recommended through this study that government should take serious initiatives to provide jobs and raise the socio-economic status of people throughout the country.